Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536798 | 0.71 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL1278939 | 0.69 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL1278642 | 0.67 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL4539698 | 0.66 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL4536193 | 0.66 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL20558903 | 0.63 | KDM4E (0.45) | — | |
| SCHEMBL20558904 | 0.63 | KDM4E (0.45) | — | |
| SCHEMBL4536153 | 0.63 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL8536021 | 0.63 | KDM4E (0.47) | — | |
| SCHEMBL4540096 | 0.62 | HCRTR1 (1.00) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638008-A1 | LACTAM DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2013-09-18 | — | — | EP | claimed |
| WO-2012063207-A1 | LACTAM DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-05-18 | — | — | WO | claimed |
| EP-2638008-A1 | LACTAM DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012063207-A1 | LACTAM DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-05-18 | — | — | WO | disclosed |