SCHEMBL453632

SCHEMBL453632

O=C(O)CNc1ccccc1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.48
KDM4E B2RXH2 3/20 0.48
MEN1 O00255 2/20 0.48
MAPT P10636 2/20 0.48
ALDH1A1 P00352 2/20 0.48
THRB P10828 1/20 0.48
ALOX12 P18054 1/20 0.48
AKR1B1 P15121 1/20 0.47
PARP1 P09874 1/20 0.46
GAA P10253 3/20 0.46
TDP1 Q9NUW8 1/20 0.46
NPC1 O15118 2/20 0.46
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 2/20 0.44
AGTR1 P30556 1/20 0.44
CA2 P00918 2/20 0.44
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30536400 1.00 KMT2A (0.48) KMT2AKDM4EMEN1MAPTALDH1A1
Hydrochloric Acid SCHEMBL28161064 1.00 KMT2A (0.48) KMT2AKDM4EMEN1MAPTALDH1A1
Ethylene SCHEMBL610090 0.96 KMT2A (0.46) KMT2AKDM4EMEN1MAPTALDH1A1
Ethylene SCHEMBL18691787 0.94 KMT2A (0.44) KMT2AKDM4EMEN1MAPTALDH1A1
Phenol SCHEMBL11266550 0.94 KMT2A (0.53) KMT2AKDM4EMEN1MAPTALDH1A1
Sulfuric Acid SCHEMBL9326880 0.93 CA1 (0.44) KMT2AKDM4EMEN1MAPTALDH1A1
SCHEMBL27977847 0.93 KMT2A (0.43) KMT2AKDM4EMEN1MAPTALDH1A1
SCHEMBL5692314 0.87 PARP1 (0.51) KMT2AKDM4EMEN1MAPTALDH1A1
Acetic Acid SCHEMBL6125418 0.85 HDAC1 (0.51) KMT2AKDM4EMAPTPARP1GAA
SCHEMBL7213300 0.85 PARP1 (0.45) KMT2AKDM4EMEN1MAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 908 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431171-A Production method of L-p-hydroxyphenylglycine methyl ester 山东优盈新材料有限公司 2025-02-14 CN claimed
CN-119350197-A Continuous process for preparing D-p-hydroxyphenylglycine double salt 浙江沙星科技股份有限公司 2025-01-24 CN claimed
CN-119330894-A Method for synthesizing HO-EPCP by catalyzing DMAP 山东鑫泉医药有限公司 2025-01-21 CN claimed
CN-116354838-B Method for recycling p-hydroxyphenylglycine and o-hydroxyphenylglycine 安徽普洛生物科技有限公司 2024-12-13 CN claimed
CN-118878433-A Preparation method of D (-) p-hydroxyphenylglycine methyl ester hydrochloride 浙江昂利康制药股份有限公司 2024-11-01 CN claimed
CN-116196980-B Ionic liquid modified epoxy resin-based immobilized metal salt catalyst, and preparation method and application thereof 天津市职业大学 2024-07-05 CN claimed
CN-118010856-A Method for detecting content of D-p-hydroxyphenylglycine 湖北省宏源药业科技股份有限公司 2024-05-10 CN claimed
CN-117999357-A Method for detecting cell stress 波士顿大学董事会 2024-05-07 CN claimed
CN-113636948-B DL-p-hydroxyphenylglycine asymmetric conversion resolution waste liquid treatment method 湖北省宏源药业科技股份有限公司 2024-04-09 CN claimed
CN-117720427-A Recovery processing method of D-p-hydroxyphenylglycine methyl ester mother liquor 山西双雁生物科技有限公司 2024-03-19 CN claimed
WO-1992012782-A1 PROCESS FOR SEPARATION OF TWO SOLID COMPONENTS NOVO NORDISK A/S (DK) 1992-08-06 WO claimed
WO-1992001061-A1 PROCESS FOR PREPARATION OF β-LACTAMS NOVO NORDISK A/S (DK) 1992-01-23 WO claimed
EP-0450684-A1 A process for the preparation of D-(-)-4-hydroxyphenylglycine and L-(+)-4-hydroxyphenylglycine, starting from D.L.-4-hydroxyphenylglycine Kessels, Gerard (ES) 1991-10-09 EP claimed
WO-1991009020-A2 PRODUCTION OF 5-(4'-HYDROXYPHENYL)HYDANTOIN AND D-p-HYDROXYPHENYLGLYCINE FROM 4-HYDROXYACETOPHENONE HOECHST CELANESE CORPORATION (US) 1991-06-27 WO claimed
US-4810259-A CHELATING AGENT OXCE FUEL COMPANY (US) 1989-03-07 US claimed
EP-0180276-A1 Dioxaphosphorinanes, their preparation and use for resolving optically active compounds STAMICARBON B.V. (NL) 1986-05-07 EP claimed
EP-0075318-A2 p-Hydroxyphenylglycine alpha-phenylethanesulfonate, process for production thereof and utilization thereof in resolution of p-hydroxyphenylglycine Tanabe Seiyaku Co., Ltd. (JP) 1983-03-30 EP claimed
US-4369146-A Method for chlorinating the carboxylic group of α-aminoacids CHIMICA BULCIAGO S.R.L. (IT) 1983-01-18 US claimed
US-4205185-A Process for preparing racemic 4-hydroxyphenylglycine STERLING DRUG INC. (US) 1980-05-27 US claimed
US-4073687-A PENICILLINS OR CEPHALOSPORINS SHIONOGI & CO., LTD. (JA) 1978-02-14 US claimed