Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4534264 | 0.95 | EPHX1 (0.54) | EPHX1EPHX2 | |
| SCHEMBL8059955 | 0.83 | EPHX2 (0.73) | EPHX1EPHX2 | |
| SCHEMBL4537216 | 0.78 | EPHX2 (0.67) | EPHX1EPHX2 | |
| SCHEMBL4537735 | 0.77 | EPHX1 (0.63) | EPHX1EPHX2 | |
| SCHEMBL8926084 | 0.75 | EPHX1 (1.00) | EPHX1EPHX2 | |
| SCHEMBL4535118 | 0.73 | EPHX2 (0.72) | EPHX1EPHX2 | |
| SCHEMBL4535609 | 0.72 | EPHX1 (0.65) | EPHX1EPHX2 | |
| SCHEMBL4541262 | 0.72 | EPHX2 (0.67) | EPHX1EPHX2 | |
| SCHEMBL4531019 | 0.71 | EPHX1 (0.58) | EPHX1EPHX2 | |
| SCHEMBL5146592 | 0.71 | EPHX1 (1.00) | EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | claimed |
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |