Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.77 |
| ▸ | HTR1A | P08908 | 5/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.57 |
| ▸ | HRH1 | P35367 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647671 | 0.96 | HRH3 (0.72) | HRH3KCNH2HTR1ASLC6A4HRH1 | |
| SCHEMBL3804486 | 0.92 | HRH3 (0.67) | HRH3KCNH2HTR1ASLC6A4HRH1 | |
| SCHEMBL4540984 | 0.90 | HRH3 (0.76) | HRH3KCNH2HTR1ASLC6A4HRH1 | |
| SCHEMBL3652444 | 0.89 | HRH3 (0.79) | HRH3KCNH2HTR1ASLC6A4HRH1 | |
| SCHEMBL3648123 | 0.87 | HRH3 (1.00) | HRH3KCNH2HTR1ASLC6A4HRH1 | |
| SCHEMBL3646448 | 0.87 | HRH3 (0.61) | HRH3KCNH2HTR1ASLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL3771831 | 0.86 | HRH3 (0.60) | HRH3KCNH2HTR1ASLC6A4HRH1 | |
| SCHEMBL3646531 | 0.86 | HRH3 (0.61) | HRH3KCNH2HTR1ASLC6A4HRH1 | |
| SCHEMBL4537082 | 0.86 | HRH3 (0.78) | HRH3KCNH2HTR1ASLC6A4HRH1 | |
| SCHEMBL3655508 | 0.85 | HRH3 (0.75) | HRH3KCNH2HTR1ASLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069300-A1 | ISOQUINOLINYL AND ISOINDOLINYL DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2009-03-12 | — | — | US | claimed |
| US-20090069300-A1 | ISOQUINOLINYL AND ISOINDOLINYL DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069300-A1 | ISOQUINOLINYL AND ISOINDOLINYL DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | HRH4, HRH3, HRH2 | HRH3 2/4885KCNH2 508/4885HTR1A 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.