Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | UBE2N | P61088 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 5/20 | 0.49 |
| ▸ | TEK | Q02763 | 4/20 | 0.49 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 4/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4531151 | 0.89 | KDM4E (0.60) | KDM4EALDH1A1HPGDUBE2NSMN1; SMN2 | |
| SCHEMBL4535596 | 0.85 | KDM4E (0.62) | KDM4EALDH1A1HPGDUBE2NSMN1; SMN2 | |
| SCHEMBL6749027 | 0.85 | KDM4E (0.62) | KDM4EALDH1A1HPGDUBE2NSMN1; SMN2 | |
| SCHEMBL4531263 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1HPGDUBE2NSMN1; SMN2 | |
| SCHEMBL4525551 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1HPGDUBE2NSMN1; SMN2 | |
| SCHEMBL4696958 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1HPGDUBE2NSMN1; SMN2 | |
| SCHEMBL14021589 | 0.81 | AURKA (0.53) | KDM4EALDH1A1HPGDUBE2NSMN1; SMN2 | |
| SCHEMBL6749778 | 0.81 | AURKA (0.53) | KDM4EALDH1A1HPGDUBE2NSMN1; SMN2 | |
| SCHEMBL4535658 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1HPGDUBE2NSMN1; SMN2 | |
| SCHEMBL4530269 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1HPGDUBE2NSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318475-A1 | Novel, Acyclically Substituted Furopyrimidine Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318475-A1 | Novel, Acyclically Substituted Furopyrimidine Derivatives and Use Thereof | DPYD, PNPO, TPMT | KDM4E 3800/4885ALDH1A1 318/4885HPGD 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.