Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989655 | 0.82 | EGFR (0.77) | EGFR | |
| SCHEMBL2998146 | 0.78 | EGFR (0.88) | EGFRERBB2 | |
| SCHEMBL3240237 | 0.77 | EGFR (0.70) | EGFRERBB2 | |
| SCHEMBL2994255 | 0.77 | EGFR (0.83) | EGFRERBB2 | |
| SCHEMBL2994148 | 0.76 | EGFR (0.79) | EGFRERBB2 | |
| SCHEMBL15876950 | 0.76 | EGFR (0.80) | EGFRERBB2 | |
| SCHEMBL2996760 | 0.76 | EGFR (0.73) | EGFRERBB2 | |
| SCHEMBL2994057 | 0.75 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL4191488 | 0.75 | EGFR (0.76) | EGFRERBB2 | |
| SCHEMBL2996621 | 0.74 | EGFR (1.00) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070328-A1 | MODULATORS OF THE EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) PATHWAY FOR USE IN THE TREATMENT OR PREVENTION OF SUBSTANCE ABUSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-06-04 | — | — | WO | disclosed |