Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | FGF23 | Q9GZV9 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3673663 | 0.77 | PARP1 (0.40) | HPGDHTTRAB9ATSHRKDM4E | |
| SCHEMBL29195098 | 0.77 | PARP1 (0.36) | HPGDNPC1RAB9AHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL27673716 | 0.75 | PARP1 (0.39) | HPGDHTTTSHRKDM4EALDH1A1 | |
| SCHEMBL23796017 | 0.73 | PARP1 (0.31) | NPC1RAB9AKDM4EPARP1MAPT | |
| SCHEMBL4537910 | 0.72 | PARP1 (0.46) | HPGDHTTFGF23ALOX12TSHR | |
| SCHEMBL1019602 | 0.70 | QPCT (0.42) | HPGDRAB9ATSHRHSD17B10KDM4E | |
| SCHEMBL1374558 | 0.70 | PRKCI (0.44) | HPGDRAB9AKDM4EALDH1A1PARP1 | |
| SCHEMBL311558 | 0.69 | PARP1 (0.40) | HPGDNPC1RAB9AHSD17B10KDM4E | |
| SCHEMBL196912 | 0.69 | PARP1 (0.42) | HPGDHSD17B10KDM4EALDH1A1PARP1 | |
| Bromide SCHEMBL14831945 | 0.68 | QPCT (0.41) | HPGDRAB9AHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638007-A2 | DRUG DERIVATIVES | Redx Pharma Limited (GB) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012063085-A2 | DRUG DERIVATIVES | REDX PHARMA LIMITED (GB) | 2012-05-18 | — | — | WO | disclosed |