Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 10/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | GPR39 | O43194 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538128 | 1.00 | MAPT (0.55) | MAPTKDM4EGAAKMT2AMEN1 | |
| SCHEMBL11190662 | 1.00 | MAPT (0.55) | MAPTKDM4EGAAKMT2AMEN1 | |
| SCHEMBL11190667 | 1.00 | MAPT (0.55) | MAPTKDM4EGAAKMT2AMEN1 | |
| SCHEMBL12474457 | 0.95 | MAPT (0.54) | MAPTKDM4EGAAKMT2AMEN1 | |
| SCHEMBL8502496 | 0.95 | MAPT (0.54) | MAPTKDM4EGAAKMT2AMEN1 | |
| SCHEMBL12474456 | 0.95 | MAPT (0.54) | MAPTKDM4EGAAKMT2AMEN1 | |
| SCHEMBL8502502 | 0.95 | MAPT (0.54) | MAPTKDM4EGAAKMT2AMEN1 | |
| SCHEMBL12474441 | 0.95 | MAPT (0.54) | MAPTKDM4EGAAKMT2AMEN1 | |
| SCHEMBL12474443 | 0.95 | MAPT (0.54) | MAPTKDM4EGAAKMT2AMEN1 | |
| SCHEMBL14386530 | 0.95 | MAPT (0.54) | MAPTKDM4EGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014041446-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC DISEASES | KANDULA MAHESH (IN) | 2014-03-20 | — | — | WO | disclosed |
| WO-2012064674-A1 | MATERIALS AND METHODS FOR IMMUNOASSAY OF PTERINS | ABBOTT LABORATORIES (US) | 2012-05-18 | — | — | WO | disclosed |