Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.69 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022080 | 1.00 | GRM5 (0.69) | GRM5PGRKCNH2 | |
| SCHEMBL16635580 | 0.88 | GRM5 (0.69) | GRM5PGRKCNH2 | |
| SCHEMBL4539080 | 0.88 | GRM5 (0.69) | GRM5PGRKCNH2 | |
| SCHEMBL5021555 | 0.88 | GRM5 (0.69) | GRM5PGRKCNH2 | |
| SCHEMBL16635581 | 0.86 | GRM5 (0.59) | GRM5PGRKCNH2 | |
| SCHEMBL16635582 | 0.86 | GRM5 (0.61) | GRM5PGRKCNH2 | |
| SCHEMBL4542095 | 0.83 | GRM5 (0.67) | GRM5PGRKCNH2 | |
| SCHEMBL16636195 | 0.83 | GRM5 (0.67) | GRM5PGRKCNH2 | |
| SCHEMBL4539727 | 0.82 | GRM5 (0.67) | GRM5PGRKCNH2 | |
| SCHEMBL4561994 | 0.81 | GRM5 (1.00) | GRM5PGRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638022-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | Bristol-Myers Squibb Company (US) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012064603-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-05-18 | — | — | WO | disclosed |