Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6071131 | 0.89 | MEN1 (0.57) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9211791 | 0.86 | NPC1 (0.63) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL10687209 | 0.85 | HTT (0.63) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL4541462 | 0.83 | SMN1; SMN2 (0.47) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL6476695 | 0.83 | MAPT (0.51) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL10400843 | 0.82 | NPC1 (0.59) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL23580995 | 0.80 | MAPT (0.64) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL29882554 | 0.80 | MAPT (0.64) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL31117171 | 0.80 | MAPT (0.67) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL10689243 | 0.79 | MAPT (1.00) | RAB9ANPC1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| EP-0846113-B1 | 1-(PYRIDYL)-PYRAZOLS AND THEIR USE AS HERBICIDES | BASF AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6107253-A | GOOD HERBICIDAL ACTION AND ARE TOLERABLE IN CROPS SUCH AS WHEAT OR RICE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-22 | — | — | US | disclosed |
| WO-1997007114-A1 | 1-(PYRIDYL)-PYRAZOLS AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-02-27 | — | — | WO | disclosed |
| US-4772312-A | PRE-AND POSTEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | disclosed |
| EP-0207285-A1 | 5-Amino-1-pyridyl-pyrazoles | BAYER AG (DE) | 1987-01-07 | — | — | EP | disclosed |