SCHEMBL454356

SCHEMBL454356

NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ODC1 P11926 1/20 0.33
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43474 1.00 MEN1 (0.38) MEN1KMT2AODC1TSHRMAPK1
SCHEMBL203118 1.00 MEN1 (0.38) MEN1KMT2AODC1TSHRMAPK1
SCHEMBL2639323 1.00 MEN1 (0.38) MEN1KMT2AODC1TSHRMAPK1
SCHEMBL202447 1.00 MEN1 (0.38) MEN1KMT2AODC1TSHRMAPK1
SCHEMBL12775011 1.00 MEN1 (0.38) MEN1KMT2AODC1TSHRMAPK1
SCHEMBL19107453 1.00 MEN1 (0.38) MEN1KMT2AODC1TSHRMAPK1
SCHEMBL23765660 1.00 MEN1 (0.38) MEN1KMT2AODC1TSHRMAPK1
SCHEMBL14745208 1.00 MEN1 (0.38) MEN1KMT2AODC1TSHRMAPK1
SCHEMBL19107454 1.00 MEN1 (0.38) MEN1KMT2AODC1TSHRMAPK1
SCHEMBL13079441 1.00 MEN1 (0.38) MEN1KMT2AODC1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190352625-A1 MUTANTS OF COCAINE ESTERASE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2019-11-21 US claimed
US-10160960-B2 Mutants of cocaine esterase THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2018-12-25 US claimed
US-20160177277-A1 MUTANTS OF COCAINE ESTERASE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2016-06-23 US claimed
US-11466063-B2 Conjugated knottin mini-proteins containing non-natural amino acids THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-10-11 US disclosed
US-20220211035-A1 METHODS TO FORMULATE NEUTRAL ORGANIC COMPOUNDS WITH POLYMER NANOPARTICLES SILICON VALLEY BANK (CA) 2022-07-07 US disclosed
US-11289238-B2 Compositions for the filling of high aspect ratio vertical interconnect access (VIA) holes HERAEUS PRECIOUS METALS NORTH AMERICA CONSHOHOCKEN LLC (US) 2022-03-29 US disclosed
EP-3378310-B1 METHODS TO PRODUCE POLYMER NANOPARTICLES AND FORMULATIONS OF ACTIVE INGREDIENTS VIVE CROP PROT INC (CA) 2021-08-04 EP disclosed
US-20210174983-A1 COMPOSITIONS FOR THE FILLING OF HIGH ASPECT RATIO VERTICAL INTERCONNECT ACCESS (VIA) HOLES HERAEUS PRECIOUS METALS NORTH AMERICA CONSHOHOCKEN LLC 2021-06-10 US disclosed
US-20200260724-A1 METHODS TO FORMULATE NEUTRAL ORGANIC COMPOUNDS WITH POLYMER NANOPARTICLES SILICON VALLEY BANK (CA) 2020-08-20 US disclosed
US-20200239531-A1 CONJUGATED KNOTTIN MINI-PROTEINS CONTAINING NON-NATURAL AMINO ACIDS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2020-07-30 US disclosed
US-20190352625-A1 MUTANTS OF COCAINE ESTERASE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2019-11-21 US disclosed
US-20130296606-A1 PRECURSOR OF POLYMERIZABLE COMPOUND FUJIFILM CORPORATION (JP) 2013-11-07 US disclosed
US-20130130904-A1 METHODS TO PRODUCE POLYMER NANOPARTICLES AND FORMULATIONS OF ACTIVE INGREDIENTS VIVE CROP PROTECTION INC. (CA) 2013-05-23 US disclosed
US-20130034650-A1 METHODS TO FORMULATE NEUTRAL ORGANIC COMPOUNDS WITH POLYMER NANOPARTICLES VIVE CROP PROTECTION INC. (CA) 2013-02-07 US disclosed
US-20120065071-A1 METHODS TO PRODUCE POLYMER NANOPARTICLES AND FORMULATIONS OF ACTIVE INGREDIENTS VIVE NANO, INC. (CA) 2012-03-15 US disclosed
US-8084397-B2 Methods to produce polymer nanoparticles and formulations of active ingredients VIVE NANO, INC. (CA) 2011-12-27 US disclosed
US-20100210465-A1 METHODS TO PRODUCE POLYMER NANOPARTICLES AND FORMULATIONS OF ACTIVE INGREDIENTS VIVE NANO, INC. (CA) 2010-08-19 US disclosed
US-20090246285-A1 MONODISPERSED ORGANIC MONOLAYER COATED CALCIUM-CONTAINING NANOPARTICLES STELLACCI FRANCESCO 2009-10-01 US disclosed
WO-2009111437-A2 MONODISPERSED ORGANIC MONOLAYER COATED CALCIUM-CONTAINING NANOPARTICLES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2009-09-11 WO disclosed
US-20080124776-A1 Carbodithioate Ligands For Nanotechnology and Methods of Use NATIONAL SCIENCE FOUNDATION 2008-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130296606-A1 PRECURSOR OF POLYMERIZABLE COMPOUND NRAS, KRAS, KSR1 MEN1 819/4885KMT2A 2586/4885ODC1 2610/4885
US-11466063-B2 Conjugated knottin mini-proteins containing non-natural amino acids ECPAS, ATRIP, ANPEP MEN1 3025/4885KMT2A 693/4885ODC1 2273/4885
US-20200239531-A1 CONJUGATED KNOTTIN MINI-PROTEINS CONTAINING NON-NATURAL AMINO ACIDS ECPAS, ATRIP, ANPEP MEN1 3025/4885KMT2A 693/4885ODC1 2273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.