⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051612 | 0.93 | EPHX1 (0.46) | — | |
| SCHEMBL10984052 | 0.91 | EPHX1 (0.50) | — | |
| SCHEMBL10488553 | 0.91 | EPHX1 (0.50) | — | |
| SCHEMBL11785337 | 0.91 | EPHX1 (0.50) | — | |
| SCHEMBL11784133 | 0.91 | EPHX1 (0.50) | — | |
| SCHEMBL11791088 | 0.91 | EPHX1 (0.50) | — | |
| SCHEMBL5425987 | 0.91 | EPHX1 (0.50) | — | |
| SCHEMBL10980778 | 0.91 | EPHX1 (0.50) | — | |
| SCHEMBL1488883 | 0.85 | — | — | |
| SCHEMBL17219 | 0.85 | KMT2A (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115463644-B | Polyacrylonitrile mercury ion adsorption resin and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-115463644-A | Polyacrylonitrile mercury ion adsorption resin and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-122010896-A | Bicyclol derivative, pharmaceutical composition thereof, preparation method and application thereof | 中国医学科学院药物研究所 | 2026-05-12 | — | — | CN | disclosed |
| CN-115463644-B | Polyacrylonitrile mercury ion adsorption resin and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-115463644-A | Polyacrylonitrile mercury ion adsorption resin and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-106866622-B | A kind of N- methyl Lomefloxacin aldehyde thiosemicarbazone derivatives and its preparation method and application | 河南大学 | 2019-03-08 | — | — | CN | disclosed |
| CN-108587613-A | A kind of preparation method of butyl thiosemicarbazide modified carbon quantum dot fluorescence probe and its application in Selective recognition copper ion | 河南工学院 | 2018-09-28 | — | — | CN | disclosed |
| EP-2240175-B1 | COMPOUNDS WITH MDR1-INVERSE ACTIVITY | US GOV HEALTH & HUMAN SERV (US) | 2013-01-02 | — | — | EP | disclosed |
| WO-2012033601-A1 | THIOSEMICARBAZONES WITH MDR1 - INVERSE ACTIVITY | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2012-03-15 | — | — | WO | disclosed |
| US-20110200557-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-08-18 | — | — | US | disclosed |
| US-20110200557-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-08-18 | — | — | US | disclosed |
| US-4492793-A | Process for the production of 2-amino-5-mercapto-1,3,4-thiadiazole | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-01-08 | — | — | US | disclosed |
| US-4456615-A | 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction | E. R. SQUIBB & SONS, INC. (US) | 1984-06-26 | — | — | US | disclosed |
| EP-0107995-A1 | 7-Oxabicycloheptane substituted amino prostaglandin analogs | E.R. Squibb & Sons, Inc. (US) | 1984-05-09 | — | — | EP | disclosed |
| US-4309426-A | Muscle-relaxant 1,3,4-thiadiazin-2-amines | RICHARDSON-MERRELL INC. (US) | 1982-01-05 | — | — | US | disclosed |
| US-4289767-A | ANTICONVULSANT, ANXIOLYTIC | RICHARDSON-MERRELL INC. (US) | 1981-09-15 | — | — | US | disclosed |
| US-4271308-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4252962-A | Process for producing 2-amino or selected 2-(substituted)amino-5-mercapto-1,3,4-thiadiazole compounds | OLIN CORPORATION (US) | 1981-02-24 | — | — | US | disclosed |
| US-4120864-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1978-10-17 | — | — | US | disclosed |
| US-3940408-A | CORROSION INHIBITORS IN LUBRICANTS | TEXACO INC. (US) | 1976-02-24 | — | — | US | disclosed |