Fluoromethane

Fluoromethane

SCHEMBL4546506

C[18F]

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11806409-B2 Imaging methods using 18F-radiolabeled biologics BRISTOL-MYERS SQUIBB COMPANY (US) 2023-11-07 US disclosed
US-20230271923-A1 IMAGING AND TARGETING PROGRAMMED DEATH LIGAND-1 (PD-LI) EXPRESSION THE JOHNS HOPKINS UNIVERSTY 2023-08-31 US disclosed
US-20230241258-A1 IMAGING METHODS USING 18F-RADIOLABELED BIOLOGICS BRISTOL-MYERS SQUIBB COMPANY 2023-08-03 US disclosed
US-20140086837-A1 F-18 RADIOLABELED COMPOUNDS FOR DIAGNOSING AND MONITORING KIDNEY FUNCTION KASINA LAILA INNOVA PHARMACEUTICALS PRIVATE LIMITED (IN) 2014-03-27 US disclosed
US-20140030189-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION CITIZENS BANK, N.A. 2014-01-30 US disclosed
US-20140017168-A1 Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules IMMUNOMEDICS, INC. (US) 2014-01-16 US disclosed
US-8557776-B2 Compounds and methods for 18F labeled agents Bayer Pharma AG (DE) 2013-10-15 US disclosed
US-8530620-B2 Radiolabelling reagents and methods GE HEALTHCARE LIMITED (GB) 2013-09-10 US disclosed
US-20130230460-A1 USE OF CYANINE DYES FOR THE DETECTION OF TAU FOR DIAGNOSIS OF EARLY-STAGE TAUOPATHIES GE HEALTHCARE LIMITED (GB) 2013-09-05 US disclosed
US-8524194-B2 Radiolabelled MMP selective compounds ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM (NL) 2013-09-03 US disclosed
US-20090035215-A1 RADIOFLUORINATION BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2009-02-05 US disclosed
US-7485283-B2 Contrast agents for myocardial perfusion imaging LANTHEUS MEDICAL IMAGING (US) 2009-02-03 US disclosed
US-20090022664-A1 Radiolabelling via fluorination of aziridines BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2009-01-22 US disclosed
US-20080292548-A1 COMPOUNDS AND METHODS FOR 18F LABELED AGENTS Lantheus Biosciences Ltd. (GB) 2008-11-27 US disclosed
US-7456202-B2 Marked maleimide compounds, method for preparing same and use thereof for marking macromolecules COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2008-11-25 US disclosed
US-20080274052-A1 RADIOFLORINATION METHODS GE HEALTHCARE LIMITED (GB) 2008-11-06 US disclosed
US-20080138283-A1 Radiolabeled compounds and uses thereof THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2008-06-12 US disclosed
US-20080112884-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING BRISTOL-MYERS SQUIBB PHARMA COMPANY 2008-05-15 US disclosed
US-7344702-B2 Contrast agents for myocardial perfusion imaging BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2008-03-18 US disclosed
US-7172749-B2 Radiolabeled irreversible inhibitors of epidermal growth factor receptor tyrosine kinase and their use in radioimaging and radiotherapy YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2007-02-06 US disclosed