SCHEMBL4546970

SCHEMBL4546970

Cc1ccc(-c2cc(-c3ccc(C)cc3)cc(-c3nc(-c4ccccc4)cc(-c4ccccc4)n3)c2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 10/20 0.66
KMT2A Q03164 10/20 0.66
HPGD P15428 8/20 0.66
ALDH1A1 P00352 7/20 0.66
MAPT P10636 7/20 0.66
KDM4E B2RXH2 6/20 0.66
TDP1 Q9NUW8 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
AGTR1 P30556 1/20 0.60
NTSR1 P30989 1/20 0.55
SLC2A1 P11166 1/20 0.50
ALDH1A3 P47895 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
GAA P10253 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CTRC Q99895 1/20 0.49
SREBF2 Q12772 1/20 0.49
CASP3 P42574 1/20 0.49
SENP8 Q96LD8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17051407 1.00 MEN1 (0.66) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL10128323 0.96 MEN1 (0.62) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL10128337 0.95 MEN1 (0.60) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL10128279 0.95 MEN1 (0.64) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL4546975 0.95 MEN1 (0.64) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL22373720 0.93 MEN1 (0.61) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL16376449 0.92 MEN1 (0.70) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL19655677 0.92 MEN1 (0.70) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL22373721 0.92 MEN1 (0.70) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL12628252 0.92 MEN1 (0.70) MEN1KMT2AHPGDALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178215-B2 Organic compound containing at least two carbazolyl-substituted phenyl structures; charge-transporting material and organic el element containing the compound PIONEER CORPORATION (JP) 2012-05-15 US disclosed
US-20090236973-A1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT PIONEER CORPORATION (JO) 2009-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090236973-A1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLCO4C1, SLCO2A1, SLCO2B1 MEN1 1984/4885KMT2A 1753/4885HPGD 2019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.