⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1960310 | 0.62 | — | — | |
| SCHEMBL1416539 | 0.62 | — | — | |
| SCHEMBL16900657 | 0.59 | — | — | |
| SCHEMBL11776166 | 0.59 | — | — | |
| SCHEMBL9605054 | 0.59 | — | — | |
| SCHEMBL19457042 | 0.59 | — | — | |
| SCHEMBL268403 | 0.59 | — | — | |
| SCHEMBL20384146 | 0.59 | — | — | |
| SCHEMBL13442812 | 0.59 | — | — | |
| SCHEMBL10028832 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318857-A1 | N,N'-Diarylurea Compounds and N,N'-Diarylthiourea Compounds as Inhibitors of Translation Initiation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2016-11-03 | — | — | US | disclosed |
| US-9421211-B2 | N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-08-23 | — | — | US | disclosed |
| US-20160060337-A1 | METHODS FOR TREATING PSORIASIS USING AN ANTI-IL-23 ANTIBODY | AMGEN INC. | 2016-03-03 | — | — | US | disclosed |
| US-20150259566-A1 | METHODS FOR PROVIDING A LOW GLOSS POLYURETHANE COATING ON A SUBSTRATE | BAYER MATERIALSCIENCE LLC (US) | 2015-09-17 | — | — | US | disclosed |
| US-20150034161-A1 | ORGANIC SEMICONDUCTING COMPOUNDS FOR USE IN ORGANIC ELECTRONIC DEVICES | NEXT ENERGY TECHNOLOGIES, INC. | 2015-02-05 | — | — | US | disclosed |
| US-20120115915-A1 | N,N'-DIARYLUREA COMPOUNDS AND N,N'-DIARYLTHIOUREA COMPOUNDS AS INHIBITORS OF TRANSLATION INITIATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-05-10 | — | — | US | disclosed |
| US-7172855-B2 | Silver halide photographic light-sensitive material and package thereof | FUJI PHOTO FILM CO., LTD. (JP) | 2007-02-06 | — | — | US | disclosed |