Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.48 |
| ▸ | FNTB | P49356 | 7/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473174 | 0.82 | FNTA (0.56) | FNTAFNTBPGGT1B | |
| SCHEMBL454713 | 0.79 | FNTA (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL455458 | 0.78 | FNTA (0.51) | FNTAFNTBPGGT1B | |
| SCHEMBL456671 | 0.75 | FNTA (0.46) | FNTAFNTBPGGT1B | |
| SCHEMBL453965 | 0.71 | FNTA (0.50) | FNTAFNTBPGGT1B | |
| SCHEMBL455701 | 0.71 | FNTA (0.48) | FNTAFNTBPGGT1B | |
| SCHEMBL7751658 | 0.71 | FNTA (0.43) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL8195498 | 0.71 | CYP11B1 (0.44) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL17301900 | 0.71 | FNTA (0.40) | FNTAFNTBPGGT1B | |
| SCHEMBL7567119 | 0.70 | FNTA (0.68) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012034038-A2 | DUAL INHIBITORS OF FARNESYLTRANSFERASE AND GERANYLGERANYLTRANSFERASE I | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2012-03-15 | — | — | WO | disclosed |