Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 16/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16365921 | 0.75 | KDM4E (0.76) | EPHX2ALOX5PRMT1KDM4EHTT | |
| SCHEMBL12932220 | 0.74 | EPHX2 (1.00) | EPHX2ALOX5HTTHDAC3HDAC1 | |
| SCHEMBL31506406 | 0.74 | EPHX2 (1.00) | EPHX2ALOX5HTTHDAC3HDAC1 | |
| SCHEMBL15741901 | 0.74 | EPHX2 (1.00) | EPHX2ALOX5HTTHDAC3HDAC1 | |
| SCHEMBL31506388 | 0.74 | EPHX2 (1.00) | EPHX2ALOX5HTTHDAC3HDAC1 | |
| SCHEMBL12932218 | 0.74 | EPHX2 (1.00) | EPHX2ALOX5HTTHDAC3HDAC1 | |
| SCHEMBL120588 | 0.74 | EPHX2 (1.00) | EPHX2ALOX5HTTHDAC3HDAC1 | |
| SCHEMBL31555412 | 0.72 | EPHX2 (0.82) | EPHX2ALOX5HDAC3HDAC1HDAC7 | |
| SCHEMBL29860462 | 0.72 | EPHX2 (0.71) | EPHX2ALOX5HDAC3HDAC1HDAC7 | |
| SCHEMBL20841984 | 0.71 | EPHX2 (0.60) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931201-B1 | USE OF SEH INHIBITORS AS ANALGESICS | UNIV CALIFORNIA (US) | 2012-05-02 | — | — | EP | disclosed |