Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2900803 | 0.98 | TSHR (0.40) | TSHRSMPD1ALDH1A1LMNADNM1 | |
| SCHEMBL11246030 | 0.91 | TSHR (0.39) | TSHRSMPD1ALDH1A1DNM1 | |
| SCHEMBL9764014 | 0.87 | CA1 (0.30) | — | |
| SCHEMBL25125852 | 0.83 | TSHR (0.43) | TSHRSMPD1ALDH1A1LMNADNM1 | |
| SCHEMBL16107215 | 0.83 | TSHR (0.43) | TSHRSMPD1ALDH1A1LMNADNM1 | |
| SCHEMBL631275 | 0.82 | MEN1 (0.34) | TSHRALDH1A1 | |
| SCHEMBL10488782 | 0.82 | TSHR (0.40) | TSHRALDH1A1 | |
| SCHEMBL15442569 | 0.82 | TSHR (0.42) | TSHRALDH1A1LMNADNM1ADH1B | |
| SCHEMBL11672964 | 0.82 | TSHR (0.42) | TSHRALDH1A1LMNADNM1ADH1B | |
| SCHEMBL11670947 | 0.82 | TSHR (0.42) | TSHRALDH1A1LMNADNM1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2613878-A1 | NOVEL OLEFIN METATHESIS CATALYSTS | Bergen Teknologioverforing AS (NO) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032131-A1 | NOVEL OLEFIN METATHESIS CATALYSTS | BERGEN TEKNOLOGIOVERFØRING AS (NO) | 2012-03-15 | — | — | WO | disclosed |