Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4549654 | 0.89 | KCNJ1 (0.69) | KCNH2KCNJ1 | |
| SCHEMBL15196790 | 0.88 | KCNH2 (0.59) | KCNH2KCNJ1 | |
| SCHEMBL4549695 | 0.85 | KCNJ1 (0.59) | KCNH2KCNJ1 | |
| SCHEMBL15196943 | 0.84 | KCNH2 (0.58) | KCNH2KCNJ1 | |
| SCHEMBL15196783 | 0.82 | KCNH2 (0.65) | KCNH2KCNJ1 | |
| SCHEMBL4549651 | 0.81 | KCNJ1 (0.69) | KCNH2KCNJ1 | |
| SCHEMBL4549696 | 0.79 | KCNJ1 (0.81) | KCNH2KCNJ1 | |
| SCHEMBL10233879 | 0.79 | KCNJ1 (0.79) | KCNH2KCNJ1 | |
| SCHEMBL15196945 | 0.77 | KCNH2 (0.64) | KCNH2KCNJ1 | |
| SCHEMBL15196780 | 0.77 | KCNH2 (0.55) | KCNH2KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058134-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | disclosed |