Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10286720 | 0.93 | KCNJ1 (0.84) | KCNJ1KCNH2 | |
| SCHEMBL4549677 | 0.86 | KCNJ1 (0.82) | KCNJ1KCNH2 | |
| SCHEMBL4549680 | 0.84 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL4549681 | 0.83 | KCNH2 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL4549676 | 0.83 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL4549673 | 0.82 | KCNJ1 (0.82) | KCNJ1KCNH2 | |
| SCHEMBL15196956 | 0.82 | KCNJ1 (0.67) | KCNJ1KCNH2 | |
| SCHEMBL4549272 | 0.76 | KCNH2 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL15196955 | 0.75 | KCNJ1 (0.65) | KCNJ1KCNH2 | |
| SCHEMBL14785684 | 0.75 | KCNH2 (0.79) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058134-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | disclosed |