Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 1.00 |
| ▸ | MAOA | P21397 | 12/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.71 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.71 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.71 |
| ▸ | SNCA | P37840 | 1/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615296 | 1.00 | MAOB (1.00) | MAOBMAOACYP1A2ADRA2AADRA2B | |
| SCHEMBL2616092 | 1.00 | MAOB (1.00) | MAOBMAOACYP1A2ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL10390089 | 0.98 | MAOB (0.97) | MAOBMAOACYP1A2ADRA2AADRA2B | |
| SCHEMBL10076400 | 0.85 | MAOB (0.73) | MAOBMAOACYP1A2ADRA2AADRA2B | |
| SCHEMBL10076445 | 0.85 | MAOB (0.73) | MAOBMAOACYP1A2ADRA2AADRA2B | |
| SCHEMBL18756752 | 0.83 | MAOB (0.71) | MAOBMAOACYP1A2ADRA2AADRA2B | |
| SCHEMBL10076415 | 0.83 | MAOB (0.71) | MAOBMAOACYP1A2ADRA2AADRA2B | |
| SCHEMBL10076418 | 0.83 | MAOB (0.71) | MAOBMAOACYP1A2ADRA2AADRA2B | |
| Selegiline SCHEMBL5499736 | 0.83 | MAOB (1.00) | MAOBMAOACYP1A2ADRA2AADRA2B | |
| Selegiline SCHEMBL1286950 | 0.83 | MAOB (1.00) | MAOBMAOACYP1A2ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589513-A | TREATMENT OF NEURODEGENERATIVE DISEASES; MONOAMINE OXIDASE INHIBITOR AND UPTAKE INHIBITOR | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1996-12-31 | — | — | US | claimed |
| EP-0509761-B1 | Transdermal composition containing selegiline | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1996-09-11 | — | — | EP | claimed |
| US-5380761-A | Containing deprenyl for treatment of Parkinson*s disease | CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1995-01-10 | — | — | US | claimed |
| EP-0509761-A1 | Transdermal composition containing selegiline | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-10-21 | — | — | EP | claimed |
| JP-6128152-A | — | — | None | — | — | JP | disclosed |
| US-10266506-B2 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PIRAMAL IMAGING SA (CH) | 2019-04-23 | — | — | US | disclosed |
| EP-2630104-B1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM | PIRAMAL IMAGING SA (CH) | 2018-04-04 | — | — | EP | disclosed |
| US-20180022719-A1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | PIRAMAL IMAGING SA (CH) | 2018-01-25 | — | — | US | disclosed |
| EP-2388245-B1 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PIRAMAL IMAGING SA (CH) | 2017-07-12 | — | — | EP | disclosed |
| US-9682944-B2 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PIRAMAL IMAGING SA (CH) | 2017-06-20 | — | — | US | disclosed |
| EP-2217549-B1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING, AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | PIRAMAL IMAGING SA (CH) | 2017-04-19 | — | — | EP | disclosed |
| EP-2450332-A1 | Compounds for use in Imaging, diagnosing and/or treatment of diseases of the central nervous system (F-D2-Deprenyl) | Bayer Pharma Aktiengesellschaft (DE) | 2012-05-09 | — | — | EP | disclosed |
| US-5589513-A | TREATMENT OF NEURODEGENERATIVE DISEASES; MONOAMINE OXIDASE INHIBITOR AND UPTAKE INHIBITOR | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1996-12-31 | — | — | US | disclosed |
| EP-0509761-B1 | Transdermal composition containing selegiline | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1996-09-11 | — | — | EP | disclosed |
| US-5380761-A | Containing deprenyl for treatment of Parkinson*s disease | CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1995-01-10 | — | — | US | disclosed |
| EP-0617615-A1 | PHARMACEUTICAL COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1994-10-05 | — | — | EP | disclosed |
| JP-H06128152-A | PERCUTANEOUS COMPOSITION | CHINOIN GYOGYSZER V T G RT | 1994-05-10 | — | — | JP | disclosed |
| WO-1993012775-A1 | PHARMACEUTICAL COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-07-08 | — | — | WO | disclosed |
| EP-0509761-A1 | Transdermal composition containing selegiline | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-10-21 | — | — | EP | disclosed |
| US-5008292-A | Pesticidal method | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1991-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022719-A1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | PMP22, MEN1, VHL | MAOB 206/4885MAOA 788/4885CYP1A2 4196/4885 |
| US-10266506-B2 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PMP22, MEN1, VHL | MAOB 206/4885MAOA 788/4885CYP1A2 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.