Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.67 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.67 |
| ▸ | LATS1 | O95835 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 9/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723366 | 0.85 | STK17B (0.67) | STK17BSTK17ALATS1BCHEBRD4 | |
| SCHEMBL11909214 | 0.85 | STK17B (0.67) | STK17BSTK17ALATS1BCHEBRD4 | |
| SCHEMBL13177678 | 0.82 | GLP1R (0.45) | STK17BSTK17AADORA2ATDP1 | |
| SCHEMBL12968578 | 0.81 | STK17A (0.62) | STK17BSTK17ALATS1BCHEBRD4 | |
| SCHEMBL4549831 | 0.81 | STK17B (0.61) | STK17BSTK17ALATS1BCHEBRD4 | |
| SCHEMBL20154729 | 0.81 | STK17B (1.00) | STK17BSTK17ALATS1BRD4MEN1 | |
| SCHEMBL23409124 | 0.79 | STK17B (0.79) | STK17BSTK17ALATS1BRD4MEN1 | |
| SCHEMBL24070647 | 0.79 | STK17B (0.75) | STK17BSTK17ABRD4TDP1 | |
| SCHEMBL3868126 | 0.79 | STK17B (0.79) | STK17BSTK17ABRD4MEN1GAA | |
| SCHEMBL13518095 | 0.78 | STK17B (0.77) | STK17BSTK17ABRD4MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061156-A1 | CDK INHIBITORS | TAVARES FRANCIS X (US) | 2012-05-10 | — | — | WO | disclosed |