Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10284931 | 0.90 | HDAC6 (0.52) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL2115332 | 0.83 | HDAC3 (0.52) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL2619365 | 0.83 | HDAC6 (0.49) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL2611208 | 0.83 | HDAC1 (0.48) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL2611374 | 0.83 | HDAC1 (0.51) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL2611334 | 0.83 | HTT (0.63) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL2611271 | 0.82 | HDAC1 (0.51) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL2611218 | 0.81 | HDAC6 (0.49) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL17540006 | 0.81 | HDAC6 (0.54) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL15832906 | 0.81 | HDAC1 (0.47) | HDAC6HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054332-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |