SCHEMBL4550108

SCHEMBL4550108

Cc1nonc1C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4546376 0.82
SCHEMBL23989366 0.79
SCHEMBL11273303 0.79
SCHEMBL10063537 0.76
SCHEMBL77219 0.71
SCHEMBL23989365 0.70
SCHEMBL24769040 0.70
SCHEMBL23989372 0.70
SCHEMBL24001025 0.70
SCHEMBL24769034 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912686-B2 LPA receptor antagonists and uses thereof GILEAD SCIENCES, INC. (US) 2024-02-27 US disclosed
US-11912686-B2 LPA receptor antagonists and uses thereof GILEAD SCIENCES, INC. (US) 2024-02-27 US disclosed
US-20240018156-A1 SPIROCYCLIC COMPOUNDS C4 THERAPEUTICS, INC. (US) 2024-01-18 US disclosed
WO-2023239750-A1 BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS C4 THERAPEUTICS, INC. (US) 2023-12-14 WO disclosed
WO-2023225664-A1 LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2023-11-23 WO disclosed
US-20230357180-A1 DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2023-11-09 US disclosed
US-20230357254-A1 IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 JANSSEN PHARMACEUTICA NV (BE) 2023-11-09 US disclosed
US-20230357254-A1 IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 JANSSEN PHARMACEUTICA NV (BE) 2023-11-09 US disclosed
US-11771689-B2 Cereblon modulators and uses thereof VIVIDION THERAPEUTICS, INC. (US) 2023-10-03 US disclosed
US-11758805-B2 Organic electroluminescence device and organometallic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-12 US disclosed
US-7781480-B2 Indole derivatives and their metal conjugates and uses thereof VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) 2010-08-24 US disclosed
US-7781480-B2 Indole derivatives and their metal conjugates and uses thereof VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) 2010-08-24 US disclosed
US-20090221564-A1 Heterocyclic Compounds and Their Use in the Treatment of Cardiovascular Disease TRIGEN LIMITED (GB) 2009-09-03 US disclosed
US-20090075978-A1 SUBSTITUTED PROPIOLIC ACID AMIDES AND THEIR USE FOR PRODUCING DRUGS GRUNENTHAL GMBH (DE) 2009-03-19 US disclosed
US-20080318939-A1 METHODS FOR TREATING OPHTHALMIC DISORDERS CYLENE PHARMACEUTICALS, INC. 2008-12-25 US disclosed
US-20080242652-A1 Indole derivatives and their metal conjugates and uses thereof VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) 2008-10-02 US disclosed
US-20080242652-A1 Indole derivatives and their metal conjugates and uses thereof VLIFE SCIENCES TECHNOLOGIES PVT. LTD. (IN) 2008-10-02 US disclosed
US-20070189865-A1 Amino cyclopropane carboxamide derivatives as bradykinin antagonists MERCK & CO., INC. 2007-08-16 US disclosed
US-20070189865-A1 Amino cyclopropane carboxamide derivatives as bradykinin antagonists MERCK & CO., INC. 2007-08-16 US disclosed
US-20070032652-A1 Methods of preparing quinolone analogs SENHWA BIOSCIENCES, INC. (TW) 2007-02-08 US disclosed