Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ROS1 | P08922 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2715164 | 0.89 | MAPT (0.47) | GSK3BMAPTROS1ALKHDAC1 | |
| SCHEMBL2716389 | 0.89 | MAPT (0.47) | GSK3BMAPTROS1ALKHDAC1 | |
| SCHEMBL2714271 | 0.88 | ROS1 (0.47) | GSK3BMAPTROS1ALKHDAC1 | |
| SCHEMBL2714487 | 0.88 | MAPT (0.47) | GSK3BMAPTROS1ALKHDAC1 | |
| SCHEMBL2713374 | 0.83 | GSK3B (0.51) | GSK3BMAPTJAK2JAK1TYK2 | |
| SCHEMBL2713191 | 0.82 | MAPT (0.46) | GSK3BMAPTROS1ALKHDAC1 | |
| SCHEMBL2715144 | 0.81 | GSK3B (0.44) | GSK3BMAPTALKHDAC1KDM1A | |
| SCHEMBL2715453 | 0.81 | MAPT (0.49) | GSK3BMAPTMAPK1JAK2JAK1 | |
| SCHEMBL2714796 | 0.80 | MAPT (0.43) | GSK3BMAPTALKHDAC1KDM1A | |
| SCHEMBL2717172 | 0.80 | MAPT (0.61) | GSK3BMAPTROS1ALKHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053186-A1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-04-26 | — | — | WO | disclosed |