Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1277393 | 0.92 | F10 (0.51) | F10F2F11HPGD | |
| SCHEMBL1277293 | 0.86 | F10 (0.54) | F10HPGD | |
| SCHEMBL1277483 | 0.85 | F10 (0.59) | F10 | |
| SCHEMBL1277428 | 0.85 | F10 (0.51) | F10F2F11HPGD | |
| SCHEMBL1277491 | 0.85 | F10 (0.51) | F10 | |
| SCHEMBL1277720 | 0.84 | F10 (0.49) | F10 | |
| SCHEMBL8232231 | 0.84 | F10 (0.52) | F10F2HPGD | |
| SCHEMBL1277302 | 0.83 | F10 (0.49) | F10HPGD | |
| SCHEMBL1277421 | 0.83 | F10 (0.49) | F10 | |
| SCHEMBL1277601 | 0.83 | F10 (0.63) | F10F2F11HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016072-A1 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007131179-A1 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-11-15 | — | — | WO | disclosed |