Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456105 | 0.81 | KDM1A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL455137 | 0.80 | HTR2A (0.30) | HTR2AHTR2CHTR2B | |
| SCHEMBL458498 | 0.78 | HTR2A (0.34) | HTR2AHTR2CHTR2B | |
| SCHEMBL458626 | 0.78 | HTR2A (0.34) | HTR2AHTR2CHTR2B | |
| SCHEMBL458138 | 0.76 | — | — | |
| SCHEMBL458933 | 0.73 | KDM1A (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL457009 | 0.73 | HTR2A (0.30) | HTR2AHTR2CHTR2B | |
| SCHEMBL1577842 | 0.71 | HTR2A (0.41) | HTR2AHTR2CHTR2B | |
| SCHEMBL1593488 | 0.71 | HTR2C (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL456867 | 0.70 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |