Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.45 |
| ▸ | GSK3A | P49840 | 13/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2714797 | 0.90 | GSK3B (0.46) | GSK3BGSK3AMAPT | |
| SCHEMBL2715626 | 0.89 | GSK3B (0.47) | GSK3BGSK3AMAPT | |
| SCHEMBL4550726 | 0.88 | MAPT (0.46) | GSK3BMAPT | |
| SCHEMBL2717064 | 0.82 | GSK3B (0.48) | GSK3BGSK3AMAPT | |
| SCHEMBL2714553 | 0.82 | GSK3B (0.48) | GSK3BGSK3AMAPT | |
| SCHEMBL2717854 | 0.79 | GSK3B (0.47) | GSK3BGSK3AMAPT | |
| SCHEMBL2715922 | 0.79 | CCR3 (0.38) | GSK3BMAPT | |
| SCHEMBL2716039 | 0.79 | MAPT (0.44) | GSK3BMAPT | |
| SCHEMBL2715586 | 0.78 | MAPT (0.56) | GSK3BMAPT | |
| SCHEMBL2716977 | 0.78 | GSK3B (0.50) | GSK3BGSK3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053186-A1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-04-26 | — | — | WO | disclosed |