Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | TDO2 | P48775 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | MPL | P40238 | 3/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14120782 | 1.00 | IDO1 (0.51) | IDO1TDO2P2RX7CYP1A2CYP3A4 | |
| SCHEMBL29656429 | 1.00 | IDO1 (0.51) | IDO1TDO2P2RX7CYP1A2CYP3A4 | |
| SCHEMBL29845425 | 1.00 | IDO1 (0.51) | IDO1TDO2P2RX7CYP1A2CYP3A4 | |
| SCHEMBL4234796 | 1.00 | IDO1 (0.51) | IDO1TDO2P2RX7CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL25358651 | 0.98 | IDO1 (0.54) | IDO1TDO2P2RX7CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL29663103 | 0.98 | IDO1 (0.54) | IDO1TDO2P2RX7CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL29830155 | 0.98 | IDO1 (0.54) | IDO1TDO2P2RX7CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL2716131 | 0.98 | IDO1 (0.54) | IDO1TDO2P2RX7CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL28965631 | 0.98 | IDO1 (0.54) | IDO1TDO2P2RX7CYP1A2CYP3A4 | |
| SCHEMBL30991168 | 0.89 | IDO1 (0.49) | IDO1TDO2P2RX7CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567298-A | Preparation method of chiral 1- (2-fluoro-3- (trifluoromethyl) phenyl) ethylamine | 上海馨远医药科技有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-117567298-B | Preparation method of chiral 1- (2-fluoro-3- (trifluoromethyl) phenyl) ethylamine | 上海馨远医药科技有限公司 | 2025-08-05 | — | — | CN | disclosed |
| CN-117567298-B | Preparation method of chiral 1- (2-fluoro-3- (trifluoromethyl) phenyl) ethylamine | 上海馨远医药科技有限公司 | 2025-08-05 | — | — | CN | disclosed |
| CN-118119600-A | SOS1 inhibitors and uses thereof | 治纳辅医药科技有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-115605476-B | Substituted tricyclic compounds | 鲁宾有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117567298-A | Preparation method of chiral 1- (2-fluoro-3- (trifluoromethyl) phenyl) ethylamine | 上海馨远医药科技有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-117567298-A | Preparation method of chiral 1- (2-fluoro-3- (trifluoromethyl) phenyl) ethylamine | 上海馨远医药科技有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-117567298-A | Preparation method of chiral 1- (2-fluoro-3- (trifluoromethyl) phenyl) ethylamine | 上海馨远医药科技有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115433196-A | Crown ether quinazoline derivative, preparation method and application thereof | 昆药集团股份有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-115368372-A | Heterocyclic quinazoline derivative, preparation method and application | 昆药集团股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-115232111-A | SOS1 degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-114835703-A | Substituted pyrimidopyridone inhibitor and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114685488-A | Compounds as SOS1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114539245-A | Pyrimidine-fused ring derivative-containing regulator, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| EP-2927218-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-07-04 | — | — | EP | disclosed |
| EP-2630122-B1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC (JP) | 2016-11-30 | — | — | EP | disclosed |
| WO-2012053186-A1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-04-26 | — | — | WO | disclosed |