Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 18/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 16/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 11/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551022 | 1.00 | DPP4 (0.43) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4388599 | 0.87 | DPP4 (0.43) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4872743 | 0.81 | DPP4 (0.47) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4866727 | 0.80 | DPP4 (0.45) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4392074 | 0.79 | DPP4 (0.44) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4870281 | 0.79 | DPP4 (0.45) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4400354 | 0.77 | DPP4 (0.49) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4390457 | 0.77 | MAPK1 (0.38) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL1509221 | 0.75 | DPP4 (0.44) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL5038240 | 0.74 | DPP4 (0.44) | DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554256-B1 | PIPERIDINO PYRIMIDINE DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OF DIABETES | MERCK & CO INC (US) | 2009-12-09 | — | — | EP | disclosed |