Methane

Methane

SCHEMBL4551206

C.NCO

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL9399695 1.00 TSHR (0.50)
SCHEMBL19053 0.93
Bromide SCHEMBL10644201 0.86
Water SCHEMBL7675567 0.86 TSHR (0.50)
Water SCHEMBL691249 0.86 TSHR (0.50)
Water SCHEMBL116947 0.86
Hydrochloric Acid SCHEMBL546549 0.86
Hydrogen Peroxide SCHEMBL4288872 0.86
SCHEMBL22440692 0.86
Water SCHEMBL5626996 0.86 TSHR (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101372496-A Corrosion inhibitor EVONIK GOLDSCHMIDT GMBH (DE) 2009-02-25 CN claimed
EP-1051172-A4 METHOD FOR TREATING COPD SMITHKLINE BEECHAM CORP (US) 2002-08-14 EP claimed
EP-1051172-A2 METHOD FOR TREATING COPD SMITHKLINE BEECHAM CORPORATION (US) 2000-11-15 EP claimed
WO-1999034798-A1 METHOD FOR TREATING COPD SMITHKLINE BEECHAM CORPORATION (US) 1999-07-15 WO claimed
WO-2009051626-A1 CEPHALOSPORIN DERIVATIVE FORMULATION JANSSEN PHARMACEUTICA, N.V. (BE) 2009-04-23 WO disclosed
CN-101372496-A Corrosion inhibitor EVONIK GOLDSCHMIDT GMBH (DE) 2009-02-25 CN disclosed
CN-1527830-A Ether derivatives useful as inhibitors of PDE4 isozymes �Ʒ� 2004-09-08 CN disclosed
CN-1518542-A Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes �Ʒ� 2004-08-04 CN disclosed
EP-1420011-A1 Compounds usefulfor treating allergic and inflammatory diseases SMITHKLINE BEECHAM CORPORATION (US) 2004-05-19 EP disclosed
EP-1380571-A1 Compounds useful for treating allergic and inflammatory diseases SMITHKLINE BEECHAM CORPORATION (US) 2004-01-14 EP disclosed
EP-0919544-B1 Compounds useful for treating allergic and inflammatory diseases SMITHKLINE BEECHAM CORP (US) 2003-05-14 EP disclosed
CN-1404480-A Pyrimidine carboxamides as inhibitors of the PDE4 isozyme PFIZER PROD INC (US) 2003-03-19 CN disclosed
EP-1051172-A4 METHOD FOR TREATING COPD SMITHKLINE BEECHAM CORP (US) 2002-08-14 EP disclosed
EP-1051172-A2 METHOD FOR TREATING COPD SMITHKLINE BEECHAM CORPORATION (US) 2000-11-15 EP disclosed
EP-1043994-A1 METHOD FOR TREATING MULTIPLE SCLEROSIS SMITHKLINE BEECHAM CORPORATION (US) 2000-10-18 EP disclosed
WO-1999034797-A1 METHOD FOR TREATING MULTIPLE SCLEROSIS SMITHKLINE BEECHAM CORPORATION (US) 1999-07-15 WO disclosed
WO-1999034798-A1 METHOD FOR TREATING COPD SMITHKLINE BEECHAM CORPORATION (US) 1999-07-15 WO disclosed
CN-1129220-A Novel crystalline cephem acid addition salts and processes for their preparation HOECHST AG (DE) 1996-08-21 CN disclosed
CN-1055363-A Process for preparing 1-dethia 2-thia cephalosporanic acid derivatives ROUSSEL UCLAF (FR) 1991-10-16 CN disclosed
CN-1048706-A 3-substituted vinyl cephalosporin derivatives and preparation method thereof EISAI CO LTD (JP) 1991-01-23 CN disclosed