SCHEMBL4551307

SCHEMBL4551307

Cc1oc(-c2ccc3c(c2)C(=O)CC3=O)nc1CCOc1cccc(CC(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.57
PPARA Q07869 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4543239 0.90 PPARG (0.54) PPARGPPARA
SCHEMBL4544273 0.89 PPARG (0.53) PPARGPPARA
SCHEMBL4543098 0.87 PPARG (0.57) PPARGPPARA
SCHEMBL4391437 0.86 PPARG (0.67) PPARGPPARA
SCHEMBL4391054 0.85 PPARG (0.75) PPARGPPARA
SCHEMBL4389715 0.85 PPARG (0.66) PPARGPPARA
SCHEMBL4391451 0.85 PPARG (0.66) PPARGPPARA
SCHEMBL4391033 0.84 PPARG (0.68) PPARGPPARA
SCHEMBL4391420 0.84 PPARG (0.65) PPARGPPARA
SCHEMBL4393357 0.84 PPARG (0.65) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1067109-B1 CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO (JP) 2009-12-09 EP claimed