Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551368 | 0.89 | RAF1 (0.46) | RAF1BRAF | |
| SCHEMBL5602980 | 0.88 | RAF1 (0.54) | RAF1BRAF | |
| SCHEMBL14473165 | 0.86 | RAF1 (0.48) | RAF1BRAF | |
| SCHEMBL5592994 | 0.85 | RAF1 (0.48) | RAF1BRAF | |
| SCHEMBL4408603 | 0.85 | RAF1 (0.48) | RAF1BRAF | |
| SCHEMBL4728328 | 0.84 | RAF1 (0.54) | RAF1BRAF | |
| SCHEMBL4419924 | 0.84 | RAF1 (0.48) | RAF1BRAF | |
| SCHEMBL4728307 | 0.78 | RAF1 (0.45) | RAF1BRAF | |
| SCHEMBL15074587 | 0.77 | PLAU (0.57) | RAF1BRAF | |
| SCHEMBL5623710 | 0.77 | RAF1 (0.50) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035005-A2 | THERAPY USING CYTOKINE INHIBITORS | Kemia, INC. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146712-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |