SCHEMBL45520

SCHEMBL45520

O=C(O)C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.56

Known targets — ChEMBL curated mechanism

ADRB2

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.56
KCNN4 O15554 7/20 0.56
NPSR1 Q6W5P4 1/20 0.50
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
CES1 P23141 1/20 0.45
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
HIF1A Q16665 1/20 0.44
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28288580 0.97 CYP1A2 (0.54) CYP1A2KCNN4NPSR1CYP2D6MAPT
SCHEMBL29559623 0.97 CYP1A2 (0.54) CYP1A2KCNN4NPSR1CYP2D6MAPT
SCHEMBL28778133 0.97 CYP1A2 (0.54) CYP1A2KCNN4NPSR1CYP2D6MAPT
SCHEMBL29282850 0.97 CYP1A2 (0.54) CYP1A2KCNN4NPSR1CYP2D6MAPT
SCHEMBL10403424 0.97 CYP1A2 (0.54) CYP1A2KCNN4NPSR1CYP2D6MAPT
SCHEMBL11522471 0.97 CYP1A2 (0.54) CYP1A2KCNN4NPSR1CYP2D6MAPT
SCHEMBL10909643 0.97 CYP1A2 (0.54) CYP1A2KCNN4NPSR1CYP2D6MAPT
SCHEMBL30541207 0.97 CYP1A2 (0.54) CYP1A2KCNN4NPSR1CYP2D6MAPT
SCHEMBL7880822 0.97 CYP1A2 (0.54) CYP1A2KCNN4NPSR1CYP2D6MAPT
Hydrogen Sulfide SCHEMBL27587806 0.97 CYP1A2 (0.54) CYP1A2KCNN4NPSR1CYP2D6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4296 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745135-A1 COMPOUND BASED ON THIO-GLUTARIMIDO ISOINDOLINONE SKELETON AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-05-20 EP claimed
EP-4745137-A1 GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-05-20 EP claimed
CN-122070278-A Bifunctional protein degradation agent containing aryl substituted heteroaryl and application thereof 标新生物医药科技(上海)有限公司 2026-05-19 CN claimed
US-20260109680-A1 METHOD FOR SYNTHESIZING 2,5-FURANDICARBOXYLIC ACID BY CARBONYLATION OF FUROIC ACID Institute of Chemical Industry of Forest Products, CAF (CN) 2026-04-23 US claimed
EP-4722207-A1 OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-04-08 EP claimed
EP-4685176-A1 2-COMPONENT FOAMS BASED ON ACETYLACETONATE AND AMINES Henkel AG & Co. KGaA (DE) 2026-01-28 EP claimed
US-12528974-B2 Polishing slurry composition KCTECH CO., LTD. (KR) 2026-01-20 US claimed
WO-2025264177-A1 METHOD FOR CLEAVING PROTECTING GROUPS AND ORGANIC COMPOUNDS FROM SUPPORTS POLYPEPTIDE LABORATORIES HOLDING (PPL) AB (SE) 2025-12-26 WO claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
EP-4452924-B1 PROCESS TO PREPARE VILANTEROL TRIFENATATE HOVIONE SCIENTIA LTD (IE) 2025-12-03 EP claimed
US-20040113127-A1 Resistor compositions having a substantially neutral temperature coefficient of resistance and methods and compositions relating thereto E.I. DU PONT DE NEMOURS AND COMPANY 2004-06-17 US claimed
CN-1501911-A Phenethanolamine derivatives for treatment of respiratory diseases 2004-06-02 CN claimed
US-20030130300-A1 Respiratory system disorders; synergistic mixtures BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-07-10 US claimed
CN-1341110-A Novel process of preparing a benzothiazolone compound ASTRAZENECA AG (SE) 2002-03-20 CN claimed
EP-0918760-B1 BIOLOGICALLY ACTIVE BENZOTHIAZOLONE ETHANAMINES ASTRAZENECA AB (SE) 2001-11-28 EP claimed
CN-1072214-C Biologically active benzothiazolone ethananines ASTRAZENECA AB (SE) 2001-10-03 CN claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0234348-B1 N-GLYCOSYL AMIDE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS BAYER AG (DE) 1991-05-29 EP claimed
US-4891425-A IMMUNOSTIMULANTS BAYER AKTIENGESELLSCHAFT (DE) 1990-01-02 US claimed
US-4332962-A RHODIUM COMPOUND AS CATALYST FOR CYCLIZATION OF A PENTADIENE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-06-01 US claimed