Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2565186 | 0.92 | MAP2K1 (0.46) | MAP2K1MAPK14 | |
| SCHEMBL2567742 | 0.83 | MAP2K1 (0.57) | MAP2K1 | |
| SCHEMBL2569318 | 0.82 | MAP2K1 (0.60) | MAP2K1 | |
| SCHEMBL2566598 | 0.82 | MAP2K1 (0.60) | MAP2K1 | |
| SCHEMBL14294967 | 0.82 | MAP2K1 (0.60) | MAP2K1 | |
| SCHEMBL2563419 | 0.77 | MAP2K1 (0.68) | MAP2K1 | |
| SCHEMBL14300141 | 0.77 | MAP2K1 (0.55) | MAP2K1MAPK14 | |
| SCHEMBL2565128 | 0.77 | MAP2K1 (0.55) | MAP2K1MAPK14 | |
| SCHEMBL2565085 | 0.77 | MAP2K1 (0.53) | MAP2K1 | |
| SCHEMBL14199457 | 0.76 | MAP2K1 (0.59) | MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069354-A1 | AZA-BENZOFURANYL COMPOUNDS AND METHODS OF USE | Genentech, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008024725-A1 | AZA-BENZOFURANYL COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2008-02-28 | — | — | WO | disclosed |