Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.71 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.63 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | AGXT | P21549 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27521276 | 0.87 | MAOB (0.77) | MAOBNR4A2PARP10MAOAIDO1 | |
| SCHEMBL3625818 | 0.84 | MAOB (0.73) | MAOBNR4A2PARP10MAOA | |
| SCHEMBL15171108 | 0.84 | MAOB (0.73) | MAOBNR4A2PARP10MAOAIDO1 | |
| SCHEMBL11959694 | 0.84 | MAOB (0.72) | MAOBNR4A2PARP10MAOAIDO1 | |
| SCHEMBL1379497 | 0.83 | MAOB (1.00) | MAOBNR4A2PARP10MAOAIDO1 | |
| SCHEMBL992837 | 0.83 | MAOB (1.00) | MAOBNR4A2PARP10 | |
| SCHEMBL21340832 | 0.83 | MAOB (0.79) | MAOBNR4A2PARP10MAOA | |
| SCHEMBL22874674 | 0.83 | MAOB (0.71) | MAOBNR4A2PARP10MAOA | |
| SCHEMBL10136590 | 0.83 | MAOB (0.71) | MAOBNR4A2PARP10MAOA | |
| SCHEMBL15156306 | 0.83 | MAOB (0.73) | MAOBNR4A2PARP10MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761480-B1 | MAO-B INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-02-18 | — | — | EP | claimed |