Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2206504 | 0.83 | HDAC1 (0.55) | HDAC1 | |
| SCHEMBL4325464 | 0.79 | HDAC1 (0.60) | HDAC1 | |
| SCHEMBL4720338 | 0.76 | KCNQ3 (0.47) | HDAC1 | |
| SCHEMBL12434721 | 0.74 | HDAC1 (0.62) | HDAC1 | |
| SCHEMBL3646097 | 0.71 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL4322107 | 0.71 | HDAC1 (0.70) | HDAC1 | |
| SCHEMBL3644778 | 0.70 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL2208872 | 0.69 | HDAC1 (0.66) | HDAC1 | |
| SCHEMBL3638632 | 0.68 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL1931064 | 0.68 | HDAC1 (0.54) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049124-A2 | PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | Merck & Co., Inc. (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008010985-A2 | PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | MERCK & CO., INC. (US) | 2008-01-24 | — | — | WO | disclosed |