Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.58 |
| ▸ | CNR1 | P21554 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610017 | 0.90 | CNR2 (0.57) | CNR2CNR1KCNH2 | |
| SCHEMBL1609361 | 0.88 | CNR2 (0.63) | CNR2CNR1KCNH2 | |
| SCHEMBL1608905 | 0.87 | CNR2 (0.64) | CNR2CNR1KCNH2 | |
| SCHEMBL1609301 | 0.87 | CNR2 (0.59) | CNR2CNR1KCNH2 | |
| SCHEMBL1608949 | 0.86 | CNR2 (0.63) | CNR2CNR1KCNH2 | |
| SCHEMBL12713963 | 0.85 | CNR2 (0.62) | CNR2CNR1KCNH2 | |
| SCHEMBL1609170 | 0.85 | CNR2 (0.59) | CNR2CNR1KCNH2 | |
| SCHEMBL1610049 | 0.85 | CNR2 (0.59) | CNR2CNR1KCNH2 | |
| SCHEMBL4551525 | 0.84 | CNR2 (0.67) | CNR2CNR1KCNH2 | |
| SCHEMBL1609630 | 0.84 | CNR2 (0.65) | CNR2CNR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010526-A1 | BENZIMIDAZOLE 5-SULFONAMIDE DERIVATIVES AS CANNABINOID 1 (CB1) RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007120101-A1 | BENZIMIDAZOLE 5-SULFONAMIDE DERIVATIVES AS CANNABINOID 1 (CB1) RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2007-10-25 | — | — | WO | disclosed |