⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315475 | 0.75 | — | — | |
| SCHEMBL2877 | 0.62 | — | — | |
| SCHEMBL3626672 | 0.60 | — | — | |
| SCHEMBL4966369 | 0.60 | — | — | |
| SCHEMBL23235576 | 0.58 | — | — | |
| SCHEMBL6671938 | 0.58 | — | — | |
| SCHEMBL1388169 | 0.58 | — | — | |
| Carbon Dioxide SCHEMBL27445899 | 0.58 | — | — | |
| SCHEMBL28995712 | 0.58 | — | — | |
| SCHEMBL4216353 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608244-B2 | Hydrophilic light absorbing compositions for determination of physiological function in critically ill patients | MALLINCKRODT INC. (US) | 2009-10-27 | — | — | US | disclosed |
| US-20090263327-A1 | MINIMALLY INVASIVE PHYSIOLOGICAL FUNCTION MONITORING AGENTS | MALLINCKRODT INC. (US) | 2009-10-22 | — | — | US | disclosed |
| US-7556797-B2 | Minimally invasive physiological function monitoring agents | MALLINCKRODT INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-7468177-B2 | Hydrophilic light absorbing compositions for determination of physiological function in critically ill patients | MALLINCKRODT INC. (US) | 2008-12-23 | — | — | US | disclosed |
| US-7438894-B2 | Dyes for organ function monitoring | MALLINCKRODT, INC. (US) | 2008-10-21 | — | — | US | disclosed |
| US-20080056989-A1 | Novel Dyes for Organ Function Monitoring | MALLINCKRODT, INC. (US) | 2008-03-06 | — | — | US | disclosed |
| US-20070269373-A1 | HYDROPHILIC LIGHT ABSORBING COMPOSITIONS FOR DETERMINATION OF PHYSIOLOGICAL FUNCTION IN CRITICALLY ILL PATIENTS | MALLINCKRODT, INC. (US) | 2007-11-22 | — | — | US | disclosed |
| US-20070269368-A1 | HYDROPHILIC LIGHT ABSORBING COMPOSITIONS FOR DETERMINATION OF PHYSIOLOGICAL FUNCTION IN CRITICALLY ILL PATIENTS | MALLINCKRODT, INC. (US) | 2007-11-22 | — | — | US | disclosed |
| US-7297325-B2 | Hydrophilic light absorbing compositions for determination of physiological function | MALLINCKRODT INC. (US) | 2007-11-20 | — | — | US | disclosed |
| US-20070140962-A1 | Light Sensitive Compounds for Instant Determination of Organ Function | MALLINCKRODT INC. (US) | 2007-06-21 | — | — | US | disclosed |
| EP-1326649-A1 | TISSUE-SPECIFIC EXOGENOUS OPTICAL AGENTS | MALLINCKRODT INC. (US) | 2003-07-16 | — | — | EP | disclosed |
| EP-1326648-A1 | NOVEL DYES FOR ORGAN FUNCTION MONITORING | Mallinckrodt Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| EP-1326650-A2 | HYDROPHILIC LIGHT ABSORBING COMPOSITIONS FOR DETERMINATION OF PHYSIOLOGICAL FUNCTION IN CRITICALLY ILL PATIENTS | Mallinckrodt Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| EP-1326647-A1 | LIGHT SENSITIVE COMPOUNDS FOR INSTANT DETERMINATION OF ORGAN FUNCTION | Mallinckrodt Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| EP-1326651-A2 | DYNAMIC ORGAN FUNCTION MONITORING AGENTS | Mallinckrodt Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032285-A2 | HYDROPHILIC LIGHT ABSORBING COMPOSITIONS FOR DETERMINATION OF PHYSIOLOGICAL FUNCTION IN CRITICALLY ILL PATIENTS | MALLINCKRODT INC. (US) | 2002-04-25 | — | — | WO | disclosed |
| WO-2002032466-A1 | LIGHT SENSITIVE COMPOUNDS FOR INSTANT DETERMINATION OF ORGAN FUNCTION | MALLINCKRODT INC. (US) | 2002-04-25 | — | — | WO | disclosed |
| WO-2002032464-A1 | NOVEL DYES FOR ORGAN FUNCTION MONITORING | MALLINCKRODT INC. (US) | 2002-04-25 | — | — | WO | disclosed |
| WO-2002032465-A1 | TISSUE-SPECIFIC EXOGENOUS OPTICAL AGENTS | MALLINCKRODT INC. (US) | 2002-04-25 | — | — | WO | disclosed |
| WO-2002032860-A2 | DYNAMIC ORGAN FUNCTION MONITORING AGENTS | MALLINCKRODT INC. (US) | 2002-04-25 | — | — | WO | disclosed |