SCHEMBL4553309

SCHEMBL4553309

CC(C)(C)c1ccc(Oc2cccc(CCCC(O[PH](=O)O)S(=O)(=O)O)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 15/20 0.59
FAAH O00519 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2066146 0.99 FDFT1 (0.58) FDFT1FAAH
SCHEMBL4553308 0.93 FDFT1 (0.60) FDFT1FAAH
SCHEMBL4294846 0.88 FDFT1 (0.55) FDFT1
SCHEMBL2066393 0.87 FDFT1 (0.54) FDFT1
SCHEMBL883945 0.86 FDFT1 (0.57) FDFT1
SCHEMBL883902 0.85 FDFT1 (0.56) FDFT1
SCHEMBL884005 0.85 FDFT1 (0.56) FDFT1
SCHEMBL2066723 0.84 FDFT1 (0.57) FDFT1
SCHEMBL10066448 0.84 FDFT1 (0.64) FDFT1FAAH
SCHEMBL884045 0.84 FDFT1 (0.57) FDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2020857-A2 ANTIMICROBIAL THERAPY FOR BACTERIAL INFECTIONS The Regents of the University of California (US) 2009-02-11 EP disclosed
WO-2007133712-A2 ANTIMICROBIAL THERAPY FOR BACTERIAL INFECTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-11-22 WO disclosed