⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8165167 | 0.86 | — | — | |
| SCHEMBL1332279 | 0.85 | — | — | |
| SCHEMBL2020 | 0.85 | — | — | |
| SCHEMBL3273872 | 0.82 | — | — | |
| SCHEMBL14964769 | 0.82 | — | — | |
| SCHEMBL7868881 | 0.81 | TDP1 (0.57) | — | |
| SCHEMBL23451826 | 0.80 | — | — | |
| SCHEMBL4800423 | 0.80 | — | — | |
| SCHEMBL4946636 | 0.80 | — | — | |
| SCHEMBL381805 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111093718-A | Therapeutic nanoconjugates and uses thereof | 巴塞罗那自治大学(UAB) | 2020-05-01 | — | — | CN | disclosed |
| US-9637515-B2 | Guggulphospholipid methods and compositions | JINA PHARMACEUTICALS, INC. (US) | 2017-05-02 | — | — | US | disclosed |
| EP-2088865-A2 | GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS | Jina Pharmaceuticals Inc. (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008058156-A9 | GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS | JINA PHARMACEUTICALS INC (US) | 2008-12-04 | — | — | WO | disclosed |
| WO-2008058156-A2 | GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS | JINA PHARMACEUTICALS INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| US-20060008813-A1 | Compositions and methods of synthesis and use of novel nucleic acid structures | ERITJA RAMON | 2006-01-12 | — | — | US | disclosed |
| EP-1556392-A1 | CARDIOLIPIN MOLECULES AND METHOD OF SYNTHESIS | Neopharm, Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| EP-1228243-A4 | COMPOSITIONS AND METHODS OF SYNTHESIS AND USE OF NOVEL NUCLEIC ACID STRUCTURES | CYGENE INC (US) | 2005-07-20 | — | — | EP | disclosed |
| US-6831072-B2 | Such as 8-amino-2'deoxyadenosine by treating 8-azido-2'deoxyadenosine with aqueous solution of methylamine or dimethylamine; for targeting nucleic acids without amplification and less use of enzymes | CYGENE, INC. | 2004-12-14 | — | — | US | disclosed |
| WO-2004039817-A1 | CARDIOLIPIN MOLECULES AND METHOD OF SYNTHESIS | NEOPHARM, INC. (US) | 2004-05-13 | — | — | WO | disclosed |
| EP-1296997-A1 | BASE ANALOGUES | Amersham Biosciences UK Limited (GB) | 2003-04-02 | — | — | EP | disclosed |
| US-20020137695-A1 | Base analogues | MEDICAL RESEARCH COUNCIL (GB) | 2002-09-26 | — | — | US | disclosed |
| EP-1228243-A1 | COMPOSITIONS AND METHODS OF SYNTHESIS AND USE OF NOVEL NUCLEIC ACID STRUCTURES | Cygene, Inc. (US) | 2002-08-07 | — | — | EP | disclosed |
| WO-2002002584-A1 | BASE ANALOGUES | AMERSHAM BIOSCIENCES UK LTD (GB) | 2002-01-10 | — | — | WO | disclosed |
| WO-2001032924-A1 | COMPOSITIONS AND METHODS OF SYNTHESIS AND USE OF NOVEL NUCLEIC ACID STRUCTURES | CYGENE, INC. (US) | 2001-05-10 | — | — | WO | disclosed |
| US-5646021-A | CLEAVAGE OF RNA | HYBRIDON, INC. (US) | 1997-07-08 | — | — | US | disclosed |
| WO-1994015620-A1 | NOVEL OLIGONUCLEOTIDES MODIFIED WITH NON-NUCLEOTIDE BRIDGING GROUPS | PHARMAGENICS, INC. (US) | 1994-07-21 | — | — | WO | disclosed |