Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13018266 | 1.00 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL13018274 | 0.90 | TRPV1 (0.63) | TRPV1 | |
| SCHEMBL3787310 | 0.86 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL13063018 | 0.84 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL3771183 | 0.83 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL3782166 | 0.80 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL3782163 | 0.80 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL4434439 | 0.80 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL3782164 | 0.80 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL3786797 | 0.77 | TRPV1 (0.44) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054411-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Amorepacific Corporation (KR) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008013414-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2008-01-31 | — | — | WO | disclosed |