⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750680 | 0.75 | — | — | |
| SCHEMBL830552 | 0.73 | — | — | |
| SCHEMBL14533362 | 0.71 | HPGD (0.40) | — | |
| SCHEMBL10414526 | 0.71 | — | — | |
| SCHEMBL18140092 | 0.67 | TDP1 (0.36) | — | |
| SCHEMBL88708 | 0.67 | — | — | |
| SCHEMBL12807550 | 0.67 | — | — | |
| SCHEMBL28886836 | 0.65 | — | — | |
| SCHEMBL8064738 | 0.63 | — | — | |
| SCHEMBL3061046 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094253-A1 | ACETAMINOPHEN COMPOSITIONS HAVING MINIMIZED SIDE EFFECTS INCLUDING REDUCED HEPATOTOXICITY | Soderling, Eric M. (US) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008073344-A1 | ACETAMINOPHEN COMPOSITIONS HAVING MINIMIZED SIDE EFFECTS INCLUDING REDUCED HEPATOTOXICITY | SODERLING ERIC M (US) | 2008-06-19 | — | — | WO | disclosed |
| US-20080139654-A1 | ACETAMINOPHEN COMPOSITIONS HAVING MINIMIZED SIDE EFFECTS INCLUDING REDUCED HEPATOTOXICITY | SODERLING ERIC MOTT | 2008-06-12 | — | — | US | disclosed |
| US-20080139654-A1 | ACETAMINOPHEN COMPOSITIONS HAVING MINIMIZED SIDE EFFECTS INCLUDING REDUCED HEPATOTOXICITY | SODERLING ERIC MOTT | 2008-06-12 | — | — | US | disclosed |