SCHEMBL4553984

SCHEMBL4553984

Fc1nn[nH]c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5276473 0.64
SCHEMBL5276957 0.61
SCHEMBL4300029 0.49
SCHEMBL22689491 0.46
SCHEMBL4311227 0.46 MEN1 (0.33)
SCHEMBL13528411 0.46
SCHEMBL7135640 0.41
SCHEMBL42968 0.35 GRIN2D (0.33)
Hydrochloric Acid SCHEMBL4178849 0.32 GRIN2D (0.31)
SCHEMBL8573290 0.32

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115286587-A High-delocalization alkali metal compound and preparation method and application thereof 珠海中科先进技术研究院有限公司 2022-11-04 CN claimed
US-8852320-B2 Preparation of metal-triazolate frameworks THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-10-07 US claimed
US-20120186449-A1 PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-07-26 US claimed
JP-6340640-A None JP disclosed
CN-115286587-B Highly delocalized alkali metal compound and preparation method and application thereof 珠海中科先进技术研究院有限公司 2024-02-23 CN disclosed
US-11814348-B2 Oxidizing liquid media for chemical transformations UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-11-14 US disclosed
CN-115286587-A High-delocalization alkali metal compound and preparation method and application thereof 珠海中科先进技术研究院有限公司 2022-11-04 CN disclosed
US-11396492-B2 Direct oxidative amination of hydrocarbons UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2022-07-26 US disclosed
US-11078136-B2 Oxidation of alkane to alkene THE SCRIPPS RESEARCH INSTITUTE (US) 2021-08-03 US disclosed
US-20210163503-A1 OXIDIZING LIQUID MEDIA FOR CHEMICAL TRANSFORMATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 2021-06-03 US disclosed
US-10858301-B2 Direct oxidation of olefins to oxygenated species THE SCRIPPS RESEARCH INSTITUTE (US) 2020-12-08 US disclosed
US-20120186449-A1 PREPARATION OF METAL-TRIAZOLATE FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-07-26 US disclosed
EP-2125859-A2 ESTRATRIENE DERIVATIVES AND THEIR USES AS 17BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS Solvay Pharmaceuticals GmbH (DE) 2009-12-02 EP disclosed
WO-2008034796-A2 ESTRATRIENE DERIVATIVES AND THEIR USES AS 17BETA-HYDR0XYSTER0ID DEHYDROGENASE INHIBITORS SOLVAY PHARMACEUTICALS GMBH (DE) 2008-03-27 WO disclosed
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed
EP-0518530-B1 Improvements in or relating to excitatory amino acid receptor antagonists LILLY CO ELI (US) 1996-10-09 EP disclosed
JP-H06340640-A PERFLUOROTRIAZINE DERIVATIVE AND ITS PRODUCTION ASAHI GLASS CO LTD 1994-12-13 JP disclosed
US-5196421-A Treatment of neurological disorders ELI LILLY AND COMPANY (US) 1993-03-23 US disclosed
EP-0518530-A2 Improvements in or relating to excitatory amino acid receptor antagonists ELI LILLY AND COMPANY (US) 1992-12-16 EP disclosed
US-5153196-A Administering for reduction of neurotransmission in nervous system disorders ELI LILLY AND COMPANY (US) 1992-10-06 US disclosed