SCHEMBL4554487

SCHEMBL4554487

CO[Si](OC)(OC1CCCCC1)OC1CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
ACHE P22303 1/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA12 O43570 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9797589 0.97
SCHEMBL11601772 0.95 NPC1 (0.32) NPC1ACHECA1CA2CA12
SCHEMBL28409059 0.92
SCHEMBL3888015 0.86
SCHEMBL20473699 0.86
SCHEMBL1322990 0.83 CA1 (0.36) NPC1ACHECA1CA2CA12
SCHEMBL19952926 0.83 CA1 (0.36) NPC1ACHECA1CA2CA12
SCHEMBL19953083 0.83 CA1 (0.36) NPC1ACHECA1CA2CA12
SCHEMBL20473702 0.80 PDGFRB (0.30)
SCHEMBL10572930 0.80 CA1 (0.32) CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7601664-B2 Olefin polymerization catalyst compositions and method of preparation UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2009-10-13 US disclosed
US-6896958-B1 Substantially transparent, abrasion-resistant films containing surface-treated nanocrystalline particles NANOPHASE TECHNOLOGIES CORPORATION (US) 2005-05-24 US disclosed
US-20050003953-A1 Olefin polymerization catalyst compositions and method of preparation W. R. GRACE & CO.-CONN. 2005-01-06 US disclosed
EP-0891387-B1 SILOXANE STAR-GRAFT POLYMERS, CERAMIC POWDERS COATED THEREWITH AND METHOD OF PREPARING COATED CERAMIC POWDERS NANOPHASE TECH CORP (US) 2004-05-26 EP disclosed
EP-1401884-A1 OLEFIN POLYMERIZATION CATALYST COMPOSITIONS AND METHOD OF PREPERATION UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2004-03-31 EP disclosed
US-20030087755-A1 Olefin polymerization catalyst compositions and method of preparation UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2003-05-08 US disclosed
WO-2002096957-A1 OLEFIN POLYMERIZATION CATALYST COMPOSITIONS AND METHOD OF PREPARATION UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2002-12-05 WO disclosed