Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555493 | 1.00 | PARP1 (1.00) | PARP1 | |
| SCHEMBL5094005 | 0.86 | PARP1 (1.00) | PARP1 | |
| SCHEMBL4555782 | 0.81 | PARP1 (1.00) | PARP1 | |
| SCHEMBL4438181 | 0.77 | PARP1 (1.00) | PARP1 | |
| SCHEMBL4555938 | 0.76 | PARP1 (1.00) | PARP1 | |
| SCHEMBL27317323 | 0.76 | PARP1 (0.59) | PARP1 | |
| SCHEMBL5090379 | 0.74 | PARP1 (1.00) | PARP1 | |
| SCHEMBL5090488 | 0.71 | PARP1 (0.69) | PARP1 | |
| SCHEMBL4445140 | 0.71 | PARP1 (1.00) | PARP1 | |
| SCHEMBL26378205 | 0.71 | HPGD (0.59) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120579-A1 | INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE | ABBOTT LABORATORIES (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008083027-A1 | INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE | ABBOTT LABORATORIES (US) | 2008-07-10 | — | — | WO | disclosed |