Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436196 | 0.84 | PARP1 (1.00) | PARP1 | |
| SCHEMBL4438172 | 0.81 | PARP1 (1.00) | PARP1 | |
| SCHEMBL2208170 | 0.81 | PARP1 (0.73) | PARP1 | |
| SCHEMBL12431790 | 0.81 | PARP1 (0.73) | PARP1 | |
| SCHEMBL2206231 | 0.80 | PARP1 (0.72) | PARP1 | |
| SCHEMBL4433426 | 0.79 | PARP1 (1.00) | PARP1 | |
| SCHEMBL4439236 | 0.78 | PARP1 (1.00) | PARP1 | |
| SCHEMBL1252294 | 0.78 | PARP1 (1.00) | PARP1 | |
| SCHEMBL15030930 | 0.78 | PARP1 (0.77) | PARP1 | |
| SCHEMBL1249701 | 0.77 | PARP1 (0.76) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120579-A1 | INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE | ABBOTT LABORATORIES (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008083027-A1 | INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE | ABBOTT LABORATORIES (US) | 2008-07-10 | — | — | WO | disclosed |