Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251210 | 1.00 | CYP2C19 (0.50) | CYP2C19TSHRLMNANFKB1PMP22 | |
| SCHEMBL9437316 | 1.00 | CYP2C19 (0.50) | CYP2C19TSHRLMNANFKB1PMP22 | |
| SCHEMBL249976 | 1.00 | CYP2C19 (0.50) | CYP2C19TSHRLMNANFKB1PMP22 | |
| SCHEMBL278372 | 1.00 | CYP2C19 (0.50) | CYP2C19TSHRLMNANFKB1PMP22 | |
| Adipic Acid SCHEMBL2227837 | 1.00 | CYP2C19 (0.50) | CYP2C19TSHRLMNANFKB1PMP22 | |
| SCHEMBL251372 | 0.98 | CYP2C19 (0.53) | CYP2C19TSHRLMNANFKB1PMP22 | |
| SCHEMBL277753 | 0.98 | CYP2C19 (0.53) | CYP2C19TSHRLMNANFKB1PMP22 | |
| SCHEMBL278034 | 0.98 | CYP2C19 (0.53) | CYP2C19TSHRLMNANFKB1PMP22 | |
| SCHEMBL251273 | 0.98 | CYP2C19 (0.53) | CYP2C19TSHRLMNANFKB1PMP22 | |
| SCHEMBL251407 | 0.98 | CYP2C19 (0.53) | CYP2C19TSHRLMNANFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1947145-B1 | Mixtures of biodegradable polyesters and products manufactured from them | NOVAMONT SPA (IT) | 2009-12-23 | — | — | EP | claimed |
| EP-1947145-A2 | Mixtures of biodegradable polyesters and products manufactured from them | NOVAMONT S.p.A. (IT) | 2008-07-23 | — | — | EP | claimed |
| EP-1360235-B1 | TERNARY MIXTURES OF BIODEGRADABLE POLYESTERS AND PRODUCTS MANUFACTURED FROM THEM | NOVAMONT SPA (IT) | 2008-05-07 | — | — | EP | claimed |
| US-7067596-B2 | Ternary mixtures of biodegradable polyesters and products manufactured from them | NOVAMONT S.P.A (IT) | 2006-06-27 | — | — | US | claimed |