SCHEMBL4555739

SCHEMBL4555739

c1noc(CCCc2ncno2)n1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.32
NCEH1 Q6PIU2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1013163 0.74
SCHEMBL23028564 0.70 CES1 (0.32) CES1NCEH1
SCHEMBL19522789 0.69 NPC1 (0.38)
SCHEMBL22173657 0.69
SCHEMBL23028560 0.68 CES1 (0.36) CES1NCEH1
SCHEMBL23028562 0.68 CES1 (0.31) CES1NCEH1
SCHEMBL23028563 0.66
SCHEMBL23028568 0.66 CA1 (0.41)
SCHEMBL11884567 0.66
SCHEMBL23028566 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2114890-A2 COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY IRM LLC (BM) 2009-11-11 EP claimed
WO-2008097428-A2 COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY IRM LLC (BM) 2008-08-14 WO claimed