SCHEMBL4556340

SCHEMBL4556340

CNS(=O)(=O)c1cccc2c(O)cccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 1/20 0.61
FTO Q9C0B1 1/20 0.54
EDNRA P25101 1/20 0.54
TSHR P16473 1/20 0.50
HCRTR1 O43613 1/20 0.47
LDHA P00338 1/20 0.47
MEN1 O00255 1/20 0.45
ESR1 P03372 1/20 0.45
GAA P10253 1/20 0.45
KMT2A Q03164 1/20 0.45
ESR2 Q92731 1/20 0.45
CDK5 Q00535 1/20 0.44
CDK5R1 Q15078 1/20 0.44
IDO1 P14902 1/20 0.44
NSD2 O96028 2/20 0.44
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 1/20 0.42
EP300 Q09472 1/20 0.42
KAT2B Q92831 1/20 0.42
KAT8 Q9H7Z6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11821856 0.88 NSD2 (0.52) FTOEDNRATSHRHCRTR1MEN1
SCHEMBL32664392 0.80 CYP1A2 (0.51) CDK2FTOTSHRHCRTR1MEN1
SCHEMBL20977444 0.79 CYP1A2 (0.50) FTOEDNRATSHRGAACDK5
SCHEMBL3165363 0.79 CDK2 (0.68) CDK2EDNRATSHRHCRTR1LDHA
SCHEMBL8893911 0.78 NSD2 (0.70) EDNRANSD2
SCHEMBL6074022 0.78 CYP3A4 (0.59) EDNRATSHRMEN1KMT2ACDK5
SCHEMBL4488183 0.77 TSHR (0.60) CDK2EDNRATSHRHCRTR1ALDH1A1
SCHEMBL3698223 0.77 HCRTR1 (0.58) EDNRATSHRHCRTR1ALDH1A1CYP1A2
SCHEMBL11813348 0.76 HTT (0.44) FTOEDNRACDK5CDK5R1NSD2
SCHEMBL30165664 0.76 CDK2 (0.70) CDK2EDNRATSHRLDHAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7541074-B2 Optical film and optical compensatory film, polarizing plate and liquid crystal display using same FUJIFILM CORPORATION (JP) 2009-06-02 US disclosed
US-20070190268-A1 Optical film and optical compensatory film, polarizing plate and liquid crystal display using same FUJI PHOTO FILM CO., LTD. (JP) 2007-08-16 US disclosed
EP-0263356-B1 PROCESS FOR THE PREPARATION OF HYDROXYNAPHTHALENE SULFONIC AMIDES BAYER AG (DE) 1991-10-02 EP disclosed
EP-0263356-A2 Process for the preparation of hydroxynaphthalene sulfonic amides BAYER AG (DE) 1988-04-13 EP disclosed